Calpain Activity Is Essential in Skin Wound Healing and Contributes to Scar Formation
Abstract
Wound healing is a multistep phenomenon that relies on complex interactions between various cell types. Calpains are ubiquitously expressed proteases regulating several processes including cellular adhesion and motility as well as inflammation and angiogenesis. Calpains can be targeted by inhibitors, and their inhibition was shown to reduce organ damage in various disease models. We aimed to assess the role of calpains in skin healing and the...
Paper Details
Title
Calpain Activity Is Essential in Skin Wound Healing and Contributes to Scar Formation
Published Date
May 16, 2012
Journal
Volume
7
Issue
5
Pages
e37084 - e37084
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