Substance P modulates properties of bone marrow-derived mesenchymal stem cells

Bone marrow derived mesenchymal stem cells (MSCs) have self-renewal characteristics and are able to differentiate into various cell types. These cells can mobilize to peripheral tissues in order to participate in important biological processes such as wound healing. They are also able to regulate hematopoietic stem cells (HSCs) trafficking between the bone marrow and the periphery through the regulation of intercellular interactions and the...