Three new cassane diterpenes from the seeds of Caesalpinia sappan

Three new cassane furanoditerpenes, phanginins N–P (1–3), together with four known ones were isolated from the seeds of Caesalpinia sappan. Their structures were elucidated on the basis of spectroscopic analysis including HRESIMS, 1D and 2D NMR techniques. Evaluation of all the compounds for cytotoxicity against three human cancer cell lines (HepG-2, MCF-7 and HCT-8) showed insignificant results (IC50 > 10...