Molecular classification of liver cirrhosis in a rat model by proteomics and bioinformatics
Abstract
Liver cirrhosis is a worldwide health problem. Reliable, noninvasive methods for early detection of liver cirrhosis are not availabe. Using a three-step approach, we classified sera from rats with liver cirrhosis following different treatment insults. The approach consisted of: (i) protein profiling using surface-enhanced laser desorption/ionization (SELDI) technology; (ii) selection of a statistically significant serum biomarker set using...
Paper Details
Title
Molecular classification of liver cirrhosis in a rat model by proteomics and bioinformatics
Published Date
Oct 1, 2004
Journal
Volume
4
Issue
10
Pages
3235 - 3245
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