Eosinophilic Inflammation, Remodeling of Lower Airway, Bronchial Responsiveness and Cough Reflex Sensitivity in Non-Asthmatic Subjects with Nasal Allergy

It has been reported that nasal allergy influences the lower airway inflammation and functions. We elucidated whether nasal allergy would contribute to lower airway inflammation and functions.266 subjects aged 21-39 years were interviewed with special emphasis on history of asthma and nasal allergies (perennial allergic rhinitis (PAR) and seasonal allergic rhinitis (Japanese cedar pollinosis; PO)). Symptomatic subject was defined when nasal...