VDAC, a multi-functional mitochondrial protein as a pharmacological target
Abstract
Regulation of mitochondrial physiology requires an efficient exchange of molecules between mitochondria and the cytoplasm via the outer mitochondrial membrane (OMM). The voltage-dependent anion channel (VDAC) lies in the OMM and forms a common pathway for the exchange of metabolites between the mitochondria and the cytosol, thus playing a crucial role in the regulation of metabolic and energetic functions of mitochondria. VDAC is also recognized...
Paper Details
Title
VDAC, a multi-functional mitochondrial protein as a pharmacological target
Published Date
Jan 1, 2012
Journal
Volume
12
Issue
1
Pages
24 - 34
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History