Lentiviral Gene Transfer of SDF-1α to Wounds Improves Diabetic Wound Healing
Abstract
Background. Chronic wounds continue to be a major clinical problem and novel therapeutic approaches are needed. We have previously demonstrated that treatment of diabetic mouse wounds with local application of stromal progenitor cells results in improved healing and increased production of stromal-derived growth factor-1 (SDF-1). We hypothesized that lentiviral-mediated increased production of SDF-1 in the wound environment could also improve...
Paper Details
Title
Lentiviral Gene Transfer of SDF-1α to Wounds Improves Diabetic Wound Healing
Published Date
Nov 1, 2007
Journal
Volume
143
Issue
1
Pages
35 - 42
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