Autophagy
Abstract
Accumulating evidence strongly suggests that autophagy, which is induced by endoplasmic reticulum (ER) stress in adipocytes, may play an important role in obesity-induced insulin resistance and type 2 diabetes. Obesity induces ER stress in mouse adipose tissue, which correlates with reduced adiponectin levels. In 3T3-L1 adipocytes, induction of ER stress is sufficient to promote autophagy-dependent adiponectin degradation. In contrast,...
Paper Details
Title
Autophagy
Published Date
Nov 16, 2010
Journal
Volume
6
Issue
8
Pages
1196 - 1197
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Notes
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