Antihypertensive Effects of Extract from Flower Buds of Coreopsis tinctoria on Spontaneously Hypertensive Rats

To provide experimental evidence for the antihypertensive activity of the flavonoids in flower buds of Coreopsis tinctoria (CT-F) and to investigate the underlying mechanism. The spontaneously hypertensive rats (SHRs) were divided into model, captopril (positive control), and CT-F groups, and the Wistar-Kyoto rats were set as control group, eight in each group. The blood pressure of SHRs, the activity of angiotensin II (Ang-II) in plasma, nitric...