Conformation-induced remote meta-C–H activation of amines
Abstract
Achieving site selectivity in carbon-hydrogen (C-H) functionalization reactions is a long-standing challenge in organic chemistry. The small differences in intrinsic reactivity of C-H bonds in any given organic molecule can lead to the activation of undesired C-H bonds by a non-selective catalyst. One solution to this problem is to distinguish C-H bonds on the basis of their location in the molecule relative to a specific functional group. In...
Paper Details
Title
Conformation-induced remote meta-C–H activation of amines
Published Date
Mar 1, 2014
Journal
Volume
507
Issue
7491
Pages
215 - 220
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