Regulation of adipogenesis and osteogenesis in mesenchymal stem cells by vascular endothelial growth factor A
Abstract
Understanding the mechanisms by which bone marrow mesenchymal stem cells (BMSCs) differentiate into bone-forming osteoblasts and marrow adipocytes is crucial to develop strategies for the treatment of several bone diseases. Age-related bone loss resulting in osteopenia and osteoporosis has been associated with reduced numbers of osteoblasts and increased numbers of adipocytes, likely originating from differentiation defects in BMSCs. Although...
Paper Details
Title
Regulation of adipogenesis and osteogenesis in mesenchymal stem cells by vascular endothelial growth factor A
Published Date
May 25, 2015
Journal
Volume
277
Issue
6
Pages
674 - 680
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Notes
History