Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors
Abstract
The proper functioning of the adult mammalian brain relies on the orchestrated regulation of neural activity by a diverse population of GABA (gamma-aminobutyric acid)-releasing neurons. Until recently, our appreciation of GABA-mediated inhibition focused predominantly on the GABA(A) (GABA type A) receptors located at synaptic contacts, which are activated in a transient or 'phasic' manner by GABA that is released from synaptic vesicles. However,...
Paper Details
Title
Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors
Published Date
Mar 1, 2005
Journal
Volume
6
Issue
3
Pages
215 - 229
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