Divergent developmental expression and function of the proton‐coupled oligopeptide transporters PepT2 and PhT1 in regional brain slices of mouse and rat

This study evaluated the developmental gene and protein expression of proton‐coupled oligopeptide transporters ( POT s: peptide transporter, PepT1 and PepT2; peptide‐histidine transporter, PhT1 and PhT2) in different regions of rodent brain, and the age‐dependent uptake of a POT substrate, glycylsarcosine (GlySar), in brain slices. Slices were obtained from cerebral cortex, cerebellum and hippocampus of wildtype and PepT2 null mice, and from...