One week treatment with salmeterol does not prevent early and late asthmatic responses and Sputum eosinophilia induced by allergen challenge in asthmatics

Salmeterol is an effective long-acting β2-agonist bronchodilator, able to inhibit, as a single dose, asthmatic responses induced by several stimuli including allergen, and the subsequent increase in sputum eosinophilia. Aim of the present study was to investigate whether these effects of salmeterol persisted after 1 week of continuous treatment, or whether a loss of the bronchoprotective effects of salmeterol can occur over time. We investigated...