Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation

Volume: 46, Pages: 270 - 279
Published: May 1, 2015
Abstract
Receptor-interacting protein 140 (RIP140) is highly expressed in the brain, and acts in neurons and microglia to affect emotional responses. The present study reveals an additional function of RIP140 in the brain, which is to regulate brain lipid homeostasis via its action in astrocytes. We found forced swim stress (FSS) significantly reduces the expression level of RIP140 and elevates cholesterol content in the brain. Mechanistically, FSS...
Paper Details
Title
Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation
Published Date
May 1, 2015
Volume
46
Pages
270 - 279
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