The Use of Local 17β-Oestradiol Treatment for Improving Vaginal Symptoms Associated with Postmenopausal Oestrogen Deficiency

The effects of local 17β-oestradiol therapy on the vaginal mucosa and endometrial thickness were studied in 35 post-menopausal women with symptoms of vaginal atrophy. Signs and symptoms of vaginal atrophy were measured by anamnesis, visual examination and the maturation index before and after 12 weeks' treatment with 17β-oestradiol in the form of vaginal tablets. The maturation proportion on vaginal smear, endometrial thickness on transvaginal...