Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer.

Volume: 185, Issue: 5, Pages: 1471 - 1486
Published: May 1, 2015
Abstract
Breast cancer metastasis is the leading cause of cancer-related deaths in women worldwide. Collagen in the tumor microenvironment plays a crucial role in regulating tumor progression. We have shown that type III collagen (Col3), a component of tumor stroma, regulates myofibroblast differentiation and scar formation after cutaneous injury. During the course of these wound-healing studies, we noted that tumors developed at a higher frequency in...
Paper Details
Title
Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer.
Published Date
May 1, 2015
Volume
185
Issue
5
Pages
1471 - 1486
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