Antimicrobial Peptides Which Exhibit Lipid Composition Dependent Membrane Binding and Sequence Dependent Efficacy of Bacteriolysis

Antimicrobial peptides are a class of short, amphiphilic peptides which are part of the innate immune system of most higher organisms. These molecules act as a first line of defense against bacterial infection, exhibiting selective recognition of bacterial pathogens over host cells and rapid killing kinetics. The studies presented focus on the antimicrobial peptide C18G which is derived from the c-terminal sequence of a human platelet factor...