Connective tissue growth factor: context-dependent functions and mechanisms of regulation.

Volume: 35, Issue: 2, Pages: 200 - 208
Published: Mar 1, 2009
Abstract
Connective tissue growth factor (CTGF, CCN2) is a secreted matricellular protein, the functions of which depend on the interactions with other molecules in the microcellular environment. As an example of context-dependent activity of CTGF, this review will outline different aspects of CTGF function in relation to angiogenesis. CTGF is barely expressed in normal adult tissue, but is strongly upregulated in fibrotic tissue and is also increased...
Paper Details
Title
Connective tissue growth factor: context-dependent functions and mechanisms of regulation.
Published Date
Mar 1, 2009
Journal
Volume
35
Issue
2
Pages
200 - 208
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