Experimental liver fibrosis research: update on animal models, legal issues and translational aspects
Abstract
Liver fibrosis is defined as excessive extracellular matrix deposition and is based on complex interactions between matrix-producing hepatic stellate cells and an abundance of liver-resident and infiltrating cells. Investigation of these processes requires in vitro and in vivo experimental work in animals. However, the use of animals in translational research will be increasingly challenged, at least in countries of the European Union, because...
Paper Details
Title
Experimental liver fibrosis research: update on animal models, legal issues and translational aspects
Published Date
Oct 1, 2013
Journal
Volume
6
Issue
1
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