Investigation of the spasmolytic activity of the flavonoid fraction of Achillea millefolium s.l. on isolated guinea-pig ilea
Abstract
The spasmolytic activity of a flavonoid fraction of a commercial sample of yarrow (Achillea millefolium s.l.), its main flavonoids as well as quercetin and two flavonoid metabolites were investigated on isolated terminal guinea-pig ilea. The aglycones quercetin, luteolin and apigenin exhibited the highest antispasmodic activities with IC50 values of 7.8 micromol/L, 9.8 micromol/L and 12.5 micromol/L, respectively. Rutin and the flavonoid...
Paper Details
Title
Investigation of the spasmolytic activity of the flavonoid fraction of Achillea millefolium s.l. on isolated guinea-pig ilea
Published Date
Dec 22, 2011
Journal
Volume
56
Issue
8
Pages
582 - 588
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