Reconstructing dynamic regulatory maps
Abstract
Even simple organisms have the ability to respond to internal and external stimuli. This response is carried out by a dynamic network of protein-DNA interactions that allows the specific regulation of genes needed for the response. We have developed a novel computational method that uses an input-output hidden Markov model to model these regulatory networks while taking into account their dynamic nature. Our method works by identifying...
Paper Details
Title
Reconstructing dynamic regulatory maps
Published Date
Jan 1, 2007
Journal
Volume
3
Issue
1
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