Matrix metalloproteinases at cancer tumor-host interface.

Volume: 19, Issue: 1, Pages: 52 - 60
Published: Feb 1, 2008
Abstract
The increasing diversity in both substrates and functions of matrix metalloproteinases (MMPs) makes these enzymes central regulators in the complex tumor ecosystem composed of cancer cells and their microenvironment. In the majority of cancers, membrane-associated and extracellular proteases are mainly produced by host cells including inflammatory cells, endothelial cells, pericytes and fibroblasts. Recent data based on in vitro and in vivo...
Paper Details
Title
Matrix metalloproteinases at cancer tumor-host interface.
Published Date
Feb 1, 2008
Volume
19
Issue
1
Pages
52 - 60
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