Autophagy regulates lipid metabolism
Abstract
The intracellular storage and utilization of lipids are critical to maintain cellular energy homeostasis. During nutrient deprivation, cellular lipids stored as triglycerides in lipid droplets are hydrolysed into fatty acids for energy. A second cellular response to starvation is the induction of autophagy, which delivers intracellular proteins and organelles sequestered in double-membrane vesicles (autophagosomes) to lysosomes for degradation...
Paper Details
Title
Autophagy regulates lipid metabolism
Published Date
Apr 1, 2009
Journal
Volume
458
Issue
7242
Pages
1131 - 1135
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