Do we Need Evidence for Everything?

There is no randomized, controlled trial (RCT) supporting the contention that evidence-based medicine is beneficial, and “evidence” is more than the information that can be obtained from RCTs. Systematic reviews have severe limitations of scope and reach, and RCTs can lead to false or contradictory conclusions. Most controlled studies enroll only highly selected groups of patients, specifically excluding those with complicating factors, yet real...