Toward quantifying the composition of soft tissues by spectral CT with Medipix3

Purpose: To determine the potential of spectral computed tomography (CT) with Medipix3 for quantifying fat, calcium, and iron in soft tissues within small animal models and surgical specimens of diseases such as fatty liver (metabolic syndrome) and unstable atherosclerosis. Methods: The spectroscopic method was applied to tomographic data acquired using a micro‐CT system incorporating a Medipix3 detector array with silicon sensor layer and...