Polymorphisms in adiposity-related genes are associated with age at menarche and menopause in breast cancer patients and healthy women

Is there any effect of genetic polymorphisms in adiposity-related genes on the timing of menarche and menopause and the total duration of menstruation among Korean women? Our results suggest that the adiposity-related genes LEP, LEPR and PPARγ may play a role in the onset and cessation of menstruation, and the total duration of menstruation. Previous candidate-gene approaches have mainly presented the results for genes related to the estrogen...