Antihistamines: topical vs oral administration
Abstract
The pathogenesis of allergic rhinitis is complex, involving not only histamine and mast cell-derived tryptase, but also eosinophil- and neutrophil-derived mediators, cytokines, and intercellular cell adhesion molecules (ICAM-1). It is surprising that antihistamines, which block only one component of the process, have proved so effective in the management of allergic rhinitis. Research has therefore focused on whether antihistamines have...
Paper Details
Title
Antihistamines: topical vs oral administration
Published Date
May 1, 1996
Volume
26
Issue
s3
Pages
11 - 17
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Notes
History