PTU-160 Second Generation Photosensitiser based Photodynamic Therapy is Efficacious and Penetrates Tissue More Deeply than Radiofrequency and Cryo- Ablative Therapies, Offering Potential for More Invasive Gastrointestinal Cancers

Introduction

Photodynamic therapy (PDT) has been used to both treat gastrointestinal (GI) cancers and for palliation. PDT has been limited by poor penetration of the laser light used to activate it. In recent years, PDT has been replaced by other minimally invasive modalities such as radiofrequency- and cryo-ablation due to fewer side effects. However, these are limited to superficial cancers. Activation of 2nd generation...