AMPK-dependent hormonal regulation of whole-body energy metabolism.

Volume: 196, Issue: 1, Pages: 115 - 127
Published: May 1, 2009
Abstract
AMP-dependent protein kinase (AMPK) is an evolutionarily conserved serine/threonine protein kinase central to the regulation of energy balance at both the cellular and whole-body levels. In its classical role as an intracellular metabolic stress-sensing kinase, AMPK switches on fatty acid oxidation and glucose uptake in muscle, while switching off hepatic gluconeogenesis. AMPK also has a broader role in metabolism through the control of...
Paper Details
Title
AMPK-dependent hormonal regulation of whole-body energy metabolism.
Published Date
May 1, 2009
Volume
196
Issue
1
Pages
115 - 127
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