An in vivo role of bone morphogenetic protein-6 in aldosterone production by rat adrenal gland

Volume: 132, Issue: 1-2, Pages: 8 - 14
Published: Oct 1, 2012
Abstract
Aldosterone is synthesized in the zona glomerulosa of the adrenal cortex. We previously reported the presence of a functional BMP system including BMP-6 in human adrenocortical cells. BMP-6 contributes to Ang II-induced aldosterone production by activating Smad signaling, in which endogenous BMP-6 action is negatively controlled by Ang II in vitro. In the present study, we examined the in vivo role of BMP-6 in regulation of aldosterone by...
Paper Details
Title
An in vivo role of bone morphogenetic protein-6 in aldosterone production by rat adrenal gland
Published Date
Oct 1, 2012
Volume
132
Issue
1-2
Pages
8 - 14
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