Prokineticin 1 mediates fetal-maternal dialogue regulating endometrial leukemia inhibitory factor
Abstract
Implantation requires communication between a receptive endometrium and a healthy blastocyst. This maternal-embryonic crosstalk involves local mediators within the uterine microenvironment. We demonstrate that a secreted protein, prokineticin 1 (PROK1), is expressed in the receptive endometrium and during early pregnancy. PROK1 induces expression of leukemia inhibitory factor (LIF) in endometrial epithelial cells and first trimester decidua via...
Paper Details
Title
Prokineticin 1 mediates fetal-maternal dialogue regulating endometrial leukemia inhibitory factor
Published Date
Jul 1, 2009
Journal
Volume
23
Issue
7
Pages
2165 - 2175
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