Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

Volume: 7, Issue: 9, Pages: 759 - 770
Published: Jul 20, 2006
Abstract
Adenosine is a key endogenous molecule that regulates tissue function by activating four G-protein-coupled adenosine receptors: A1, A2A, A2B and A3. Cells of the immune system express these receptors and are responsive to the modulatory effects of adenosine in an inflammatory environment. Animal models of asthma, ischaemia, arthritis, sepsis, inflammatory bowel disease and wound healing have helped to elucidate the regulatory roles of the...
Paper Details
Title
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
Published Date
Jul 20, 2006
Volume
7
Issue
9
Pages
759 - 770
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