Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

Volume: 101, Issue: 7, Pages: 2082 - 2087
Published: Feb 17, 2004
Abstract
In the liver, insulin controls both lipid and glucose metabolism through its cell surface receptor and intracellular mediators such as phosphatidylinositol 3-kinase and serine-threonine kinase AKT. The insulin signaling pathway is further modulated by protein tyrosine phosphatase or lipid phosphatase. Here, we investigated the function of phosphatase and tension homologue deleted on chromosome 10 (PTEN), a negative regulator of the...
Paper Details
Title
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity
Published Date
Feb 17, 2004
Volume
101
Issue
7
Pages
2082 - 2087
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.