Connecting Wounds with Connexins

In this issue, Brandner et al have extended previous observations on changes in connexin distribution during skin wound healing and have also proposed that keratinocytes grafted into a wound bed might help to reconstitute a tissue gap junction network dominated by connexins 26 and 30 (hyperproliferative connexins). These findings alert us to the possibility that targeting of specific connexins could provide a new approach to improving therapy of...