The FXR agonist 6ECDCA reduces hepatic steatosis and oxidative stress induced by ethanol and low-protein diet in mice
Abstract
Background and aim: Excessive ethanol consumption can lead to development of hepatic steatosis. Since the FXR receptor regulates adipose cell function and liver lipid metabolism, the aim of this work was to examine the effects of the FXR agonist 6ECDCA on alcoholic liver steatosis development and on oxidative stress induced by ethanol consumption. Methods: Swiss mice (n = 24) received a low-protein diet (6%) and a liquid diet containing 10%...
Paper Details
Title
The FXR agonist 6ECDCA reduces hepatic steatosis and oxidative stress induced by ethanol and low-protein diet in mice
Published Date
Jun 1, 2014
Volume
217
Pages
19 - 27
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