Dynamics of tumor cell clonogen repopulation in a murine sarcoma treated with cyclophosphamide
Abstract
Experiments were performed to establish the extent and kinetics of tumor cell repopulation in a murine sarcoma, designated SA-NH, treated with cyclophosphamide (CY). Mice bearing 8-mm leg tumors were treated with 200 mg/kg CY which caused a transient tumor regression. Changes in the absolute clonogen content of tumors was determined by the change in TCD50 values (50% tumor control) obtained under hypoxic conditions of local tumor irradiation at...
Paper Details
Title
Dynamics of tumor cell clonogen repopulation in a murine sarcoma treated with cyclophosphamide
Published Date
Mar 1, 1994
Journal
Volume
30
Issue
3
Pages
247 - 253
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