Rosmarinic acid attenuates hepatic ischemia and reperfusion injury in rats
Abstract
Rosmarinic acid (RosmA) demonstrates antioxidant and anti-inflammatory properties. We investigated the effect of RosmA on liver ischemia/reperfusion injury. Rats were submitted to 60 min of ischemia plus saline or RosmA treatment (150 mg/kg BW intraperitoneally) followed by 6 h of reperfusion. Hepatocellular injury was evaluated according to aminotransferase activity and histological damage. Hepatic neutrophil accumulation was also evaluated....
Paper Details
Title
Rosmarinic acid attenuates hepatic ischemia and reperfusion injury in rats
Published Date
Dec 1, 2014
Journal
Volume
74
Pages
270 - 278
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