Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress
Abstract
Although DNA damage in human spermatozoa is associated with adverse health effects, its origin is not fully understood. Therefore, we assessed biomarkers in ejaculates that retrospectively reflect processes that occurred in the epididymis or testis. Smoking increased the amount of DNA strand breaks (P<0.01), and enhanced the presence of vitamin C radicals in seminal plasma. In vitro, vitamin C protected mature spermatozoa against DNA damage, but...
Paper Details
Title
Incomplete protection of genetic integrity of mature spermatozoa against oxidative stress
Published Date
Jul 1, 2011
Journal
Volume
32
Issue
1
Pages
106 - 111
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