Comparison of Conventional-Dose vs High-Dose Conformal Radiation Therapy in Clinically Localized Adenocarcinoma of the Prostate

ContextClinically localized prostate cancer is very prevalent among US men, but recurrence after treatment with conventional radiation therapy is common.ObjectiveTo evaluate the hypothesis that increasing the radiation dose delivered to men with clinically localized prostate cancer improves disease outcome.Design, Setting, and PatientsRandomized controlled trial of 393 patients with stage T1b through T2b prostate cancer and prostate-specific...