Platelet lysate stimulates wound repair of HaCaT keratinocytes

Platelets play a pivotal role in wound healing. Their beneficial effect is attributed to the release of bioactive substances, although the involved mechanisms are mostly unknown.To investigate mechanisms underlying platelet-induced wound healing using HaCaT keratinocytes, representing an in vitro model of proliferating and migrating keratinocytes.Cells were exposed to platelet lysate (PL) purified from whole blood samples. Cell metabolism and...