Synthesis and antioxidant activity of hydroxylated phenanthrenes as cis-restricted resveratrol analogues
Abstract
Five hydroxylated phenanthrenes as "cis-configuration-fixed" resveratrol analogues differing in the number and position of the hydroxyl groups were designed and synthesized. Their antioxidant activity was studied by ferric reducing antioxidant power, 2,2-diphenyl-1-picrylhydrazyl free radical-scavenging, and DNA strand breakage-inhibiting assays, corresponding to their electron-donating, hydrogen-transfer and DNA-protecting abilities,...
Paper Details
Title
Synthesis and antioxidant activity of hydroxylated phenanthrenes as cis-restricted resveratrol analogues
Published Date
Dec 1, 2012
Journal
Volume
135
Issue
3
Pages
1011 - 1019
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