Anticancer activities of diphenyl difluoroketone, a novel curcumin analog, on KB human oral cancer cells

Volume: 55, Issue: 4, Pages: 451 - 456
Published: Aug 1, 2012
Abstract
Effects of diphenyl difluoroketone (EF-24) and curcumin on cell growth and apoptosis induction in KB human oral cancer cells were examined. EF-24 and curcumin inhibited the growth of KB cells in a dose-dependent manner, and the potency of EF-24 was 30 times greater than that of curcumin. Treatment with EF-24 or curcumin resulted in nuclear condensation and fragmentation. EF-24 and curcumin promoted the proteolytic cleavage of procaspases-3, -7,...
Paper Details
Title
Anticancer activities of diphenyl difluoroketone, a novel curcumin analog, on KB human oral cancer cells
Published Date
Aug 1, 2012
Volume
55
Issue
4
Pages
451 - 456
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