Emerging roles of ADAM and ADAMTS metalloproteinases in cancer

Volume: 90, Issue: 2, Pages: 369 - 379
Published: Feb 1, 2008
Abstract
A disintegrin and metalloproteinases (ADAMs) are a recently discovered family of proteins that share the metalloproteinase domain with matrix metalloproteinases (MMPs). Among this family, structural features distinguish the membrane-anchored ADAMs and the secreted ADAMs with thrombospondin motifs referred to as ADAMTSs. By acting on a large panel of membrane-associated and extracellular substrates, they control several cell functions such as...
Paper Details
Title
Emerging roles of ADAM and ADAMTS metalloproteinases in cancer
Published Date
Feb 1, 2008
Journal
Volume
90
Issue
2
Pages
369 - 379
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