Host–bacterial interactions and the pathogenesis of Helicobacter pylori infection

Helicobacter pylori is a human-specific gastric pathogen that colonizes the stomachs of at least half the world's population[ 1 Blaser M.J. J. Clin. Invest. 1997; 100: 759-762 Crossref PubMed Scopus (95) Google Scholar ]. Most infected individuals are asymptomatic; however, for a significant number of individuals, infection with H. pylori is associated with the development of gastritis, gastric glandular atrophy, duodenal and gastric ulcers,...