Allergic reaction to hyaluronidase after a peribulbar injection

Hyaluronidase is a testicular protein, which hydrolyses hyaluronic acid, a structural component of the intercellular ground substance. It is often mixed in the local anaesthetic solutions used in ophthalmic regional anaesthetic techniques in order to improve the anaesthetic action in terms of speed of onset and spread of block. It is known to be a potential cause of allergic adverse events although there are few reports and little detail in the...