Automated Reference Region Extraction and Population-Based Input Function for Brain [11C]TMSX PET Image Analyses
Volume: 35, Issue: 1, Pages: 157 - 165
Published: Nov 5, 2014
Abstract
[(11)C]TMSX ([7-N-methyl-(11)C]-(E)-8-(3,4,5-trimethoxystyryl)-1,3,7-trimethylxanthine) is a selective adenosine A2A receptor (A2AR) radioligand. In the central nervous system (CNS), A2AR are linked to dopamine D2 receptor function in striatum, but they are also important modulators of inflammation. The golden standard for kinetic modeling of brain [(11)C]TMSX positron emission tomography (PET) is to obtain arterial input function via arterial...
Paper Details
Title
Automated Reference Region Extraction and Population-Based Input Function for Brain [11C]TMSX PET Image Analyses
Published Date
Nov 5, 2014
Volume
35
Issue
1
Pages
157 - 165
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