Modulation of accelerated repopulation in mouse skin during daily irradiation

Background and purpose: The timing of acceleration of repopulation in the epidermis during daily irradiation is related to the development of skin erythema and epidermal hypoplasia. Therefore, the relationship between impairment of the epidermal barrier function, the dermal inflammatory response and epidermal hypoplasia with the acceleration of repopulation was investigated. Materials and purpose: Skin fields of approximately 1 cm2 on the thighs...