Neural circuitry engaged by prostaglandins during the sickness syndrome
Abstract
During illnesses caused by infectious disease or other sources of inflammation, a suite of brain-mediated responses called the sickness syndrome occurs, which includes fever, anorexia, sleepiness, hyperalgesia and elevated corticosteroid secretion. Much of the sickness syndrome is mediated by prostaglandins acting on the brain and can be prevented by nonsteroidal anti-inflammatory drugs, such as aspirin or ibuprofen, that block prostaglandin...
Paper Details
Title
Neural circuitry engaged by prostaglandins during the sickness syndrome
Published Date
Jul 26, 2012
Journal
Volume
15
Issue
8
Pages
1088 - 1095
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