Do Margins Matter? The Influence of Positive Surgical Margins on Prostate Cancer–Specific Mortality

Positive surgical margins (PSMs) in radical prostatectomy (RP) specimens are a frequent indication for adjuvant radiotherapy and are used as a measure of surgical quality. However, the association between PSMs and prostate cancer–specific mortality (CSM) is poorly defined. Analyze the association of PSMs with CSM, adjusting for fixed and time-dependent parameters. Fine and Gray competing risk regression analysis was used to model the clinical...